Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.43 |
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512135 | 1.00 | CNR1 (0.43) | CNR1CNR2MAPTTP53SMN1; SMN2 | |
| SCHEMBL24512273 | 0.87 | CNR1 (0.46) | CNR1CNR2MAPTTP53SMN1; SMN2 | |
| SCHEMBL30899272 | 0.87 | CNR1 (0.46) | CNR1CNR2MAPTTP53SMN1; SMN2 | |
| SCHEMBL29717111 | 0.80 | CNR1 (0.64) | CNR1CNR2MAPTTP53SMN1; SMN2 | |
| SCHEMBL24512245 | 0.80 | CNR1 (0.64) | CNR1CNR2MAPTTP53SMN1; SMN2 | |
| SCHEMBL24512359 | 0.78 | CNR1 (0.46) | CNR1CNR2MAPTTP53SMN1; SMN2 | |
| SCHEMBL24512121 | 0.78 | CNR1 (0.46) | CNR1CNR2MAPTTP53SMN1; SMN2 | |
| SCHEMBL24512143 | 0.77 | MAP4K1 (0.35) | CNR1CNR2LMNAHPGD | |
| SCHEMBL24512243 | 0.76 | CNR1 (0.41) | CNR1CNR2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29717158 | 0.76 | CNR1 (0.41) | CNR1CNR2MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915903-A | Compounds for the treatment of neurodegenerative, degenerative and metabolic disorders and uses thereof | 佛罗里达大学研究基金会公司 | 2024-04-19 | — | — | CN | disclosed |