SCHEMBL3089956

SCHEMBL3089956

CC(=NNc1ccccc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 2/20 0.60
ALDH1A1 P00352 7/20 0.56
MAPT P10636 6/20 0.56
KMT2A Q03164 6/20 0.56
MEN1 O00255 4/20 0.56
RAB9A P51151 4/20 0.56
NPC1 O15118 3/20 0.56
KDM4E B2RXH2 2/20 0.56
GLA P06280 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
GAA P10253 9/20 0.51
RECQL P46063 1/20 0.51
NAPRT Q6XQN6 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HTT P42858 1/20 0.47
HPGD P15428 2/20 0.45
LMNA P02545 2/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX5 P09917 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6674219 1.00 GFER (0.60) GFERALDH1A1MAPTKMT2AMEN1
Phenylhydrazine SCHEMBL28003963 0.91 GFER (0.53) GFERALDH1A1MAPTKMT2AMEN1
SCHEMBL11756546 0.88 GFER (0.57) GFERALDH1A1MAPTKMT2AMEN1
SCHEMBL9429111 0.84 TDP1 (0.48) GFERALDH1A1MAPTKMT2AMEN1
SCHEMBL9429115 0.84 TDP1 (0.48) GFERALDH1A1MAPTKMT2AMEN1
SCHEMBL8476492 0.84 GFER (0.57) GFERALDH1A1MAPTKMT2AMEN1
SCHEMBL28003579 0.83 MAPT (0.59) GFERALDH1A1MAPTKMT2AMEN1
SCHEMBL28003931 0.83 GAA (0.46) GFERALDH1A1MAPTKMT2AMEN1
SCHEMBL23540865 0.82 ALDH1A1 (0.50) GFERALDH1A1MAPTKMT2AMEN1
SCHEMBL2172551 0.82 MAPT (0.58) GFERALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0937714-B1 Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM IP ASSETS BV (NL) 2004-10-06 EP claimed
US-6121460-A Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM N.V. (NL) 2000-09-19 US claimed
EP-0937714-A1 Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM N.V. (NL) 1999-08-25 EP claimed
CN-119745886-A Application of 4-isopropylphenyl acetylpiperazine in preparation of anti-Alzheimer disease drugs 中国药科大学 2025-04-04 CN disclosed
CN-119111439-A Method for judging activity of young crabs and application 南京师范大学 2024-12-13 CN disclosed
CN-115104672-B Aronia melanocarpa pellet feed and preparation method and application thereof 诺维特星盟饲料科技(辽宁)有限公司 2024-10-29 CN disclosed
CN-118141797-A Application of retigabine in preparing medicine for treating non-alcoholic fatty liver disease 上海市第六人民医院 2024-06-07 CN disclosed
CN-117942351-A Use of hydrogen storage materials for the preparation of articles for wound treatment or skin care 北京工业大学 2024-04-30 CN disclosed
CN-117379371-A Mugwort leaf volatile oil microemulsion gel and preparation method and application thereof 河南中医药大学 2024-01-12 CN disclosed
CN-115104672-A Aronia melanocarpa pellet feed as well as preparation method and application thereof 沈阳师范大学 2022-09-27 CN disclosed
CN-114533820-A Method for improving yield of total flavone and total polysaccharide in water extract of anoectochilus formosanus and application 北京中医药大学 2022-05-27 CN disclosed
US-20080124568-A1 New flux composition and process for use thereof GLOBALFOUNDRIES INC. (KY) 2008-05-29 US disclosed
EP-0937714-B1 Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM IP ASSETS BV (NL) 2004-10-06 EP disclosed
CN-1086205-C Kit for determining alanine aminopherase YUANDONG XIEHE BIOLOG TECHNOLO (CN) 2002-06-12 CN disclosed
US-6121460-A Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM N.V. (NL) 2000-09-19 US disclosed
US-6121460-A Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM N.V. (NL) 2000-09-19 US disclosed
CN-1231341-A Kit for determining alanine aminopherase YUANDONG XIEHE BIOLOG TECHNOLO (CN) 1999-10-13 CN disclosed
EP-0937714-A1 Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM N.V. (NL) 1999-08-25 EP disclosed
EP-0937714-A1 Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM N.V. (NL) 1999-08-25 EP disclosed
US-4008217-A HERBICIDE THE UPJOHN COMPANY (US) 1977-02-15 US disclosed