Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.60 |
| ▸ | SKP1 | P63208 | 2/20 | 0.60 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30365856 | 1.00 | CKS1B (0.60) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL14523362 | 0.86 | CKS1B (0.58) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL20163032 | 0.82 | CKS1B (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL22118550 | 0.81 | MAP4K4 (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL29435004 | 0.81 | MAP4K4 (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL30376692 | 0.81 | CKS1B (0.57) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL3294544 | 0.81 | CKS1B (0.57) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL14614610 | 0.80 | CKS1B (0.59) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL14523391 | 0.80 | CKS1B (0.66) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL1432688 | 0.80 | CKS1B (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076604-A | Pyrazolo [3,4-b ] pyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2024-05-24 | — | — | CN | disclosed |