Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.43 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30365847 | 1.00 | GRM5 (0.52) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL169492 | 0.92 | GRM5 (0.48) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL13490526 | 0.88 | GRM5 (0.53) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL171485 | 0.87 | GRM5 (0.52) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL1577496 | 0.87 | GRM5 (0.52) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL171369 | 0.87 | GRM5 (0.52) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL13490532 | 0.87 | GRM5 (0.52) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL13490533 | 0.85 | GRM5 (0.50) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL13490670 | 0.85 | GRM5 (0.52) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL4010552 | 0.84 | GRM5 (0.64) | GRM5LNPEPPRMT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076604-A | Pyrazolo [3,4-b ] pyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2024-05-24 | — | — | CN | disclosed |