SCHEMBL171369

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL171387	0.94	GRM5 (0.48)	GRM5LNPEPPRMT5WNT3APRMT1
	SCHEMBL169492	0.94	GRM5 (0.48)	GRM5LNPEPPRMT5WNT3APRMT1
	SCHEMBL13490526	0.88	GRM5 (0.53)	GRM5LNPEPPRMT5WNT3APRMT1
	SCHEMBL13490532	0.87	GRM5 (0.52)	GRM5LNPEPPRMT5WNT3APRMT1
	SCHEMBL171485	0.87	GRM5 (0.52)	GRM5LNPEPPRMT5PRMT1MEN1
	SCHEMBL1577496	0.87	GRM5 (0.52)	GRM5LNPEPPRMT5WNT3APRMT1
	SCHEMBL30899650	0.87	GRM5 (0.52)	GRM5LNPEPPRMT5PRMT1MEN1
	SCHEMBL30365847	0.87	GRM5 (0.52)	GRM5LNPEPPRMT5PRMT1MEN1
	SCHEMBL13490533	0.85	GRM5 (0.50)	GRM5LNPEPPRMT5PRMT1MEN1
	SCHEMBL8315932	0.85	MEN1 (0.57)	GRM5LNPEPPRMT1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.