Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044214 | 0.99 | MEN1 (0.57) | MEN1KMT2ANPSR1HPGDCD274 | |
| SCHEMBL1463825 | 0.90 | POLB (0.61) | MEN1KMT2ANPSR1LMNASMN1; SMN2 | |
| SCHEMBL7159219 | 0.89 | LMNA (0.63) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20718021 | 0.85 | SMN1; SMN2 (0.58) | MEN1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL3622367 | 0.84 | KMT2A (0.53) | KMT2AHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8703529 | 0.84 | KAT2B (0.58) | LMNASMN1; SMN2HTT | |
| SCHEMBL28546176 | 0.84 | LMNA (0.57) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL31287201 | 0.84 | GAA (0.58) | MEN1KMT2ALMNASMN1; SMN2SIRT2 | |
| SCHEMBL29889010 | 0.84 | SMN1; SMN2 (0.51) | MEN1KMT2ALMNASMN1; SMN2CYP3A4 | |
| SCHEMBL31697361 | 0.83 | LMNA (0.56) | MEN1KMT2ANPSR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112744-A1 | CATALYSTS AND METHODS OF USE THEREOF | YALE UNIVERSITY (US) | 2024-05-30 | — | — | WO | disclosed |