Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.45 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16533373 | 0.79 | ALDH1A1 (0.41) | CYP1A2ALDH1A1RAB9A | |
| SCHEMBL12465690 | 0.77 | ALDH1A1 (0.48) | PTGER1SMPD1ALDH1A1RAB9A | |
| SCHEMBL32675245 | 0.77 | MAOB (0.47) | HDAC1HDAC8HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL30134395 | 0.77 | SLC6A4 (0.53) | LMNASLC6A4PTGER1CCR5HTR2C | |
| SCHEMBL22116580 | 0.76 | MRGPRX4 (0.48) | LMNALRRK2PTGER1RAB9A | |
| SCHEMBL30504080 | 0.75 | SLC6A4 (0.59) | SLC6A4CCR5SMPD1HDAC1HDAC8 | |
| SCHEMBL1447864 | 0.75 | SLC6A4 (0.59) | SLC6A4CCR5SMPD1HDAC1HDAC8 | |
| SCHEMBL24233947 | 0.75 | MRGPRX4 (0.44) | LMNALRRK2PTGER1ALDH1A1RAB9A | |
| SCHEMBL368071 | 0.75 | SLC6A4 (0.66) | LMNASLC6A4PTGER1CCR5USP28 | |
| SCHEMBL31644088 | 0.75 | SLC6A4 (0.66) | LMNASLC6A4PTGER1CCR5USP28 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119033-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-20240300951-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-09-12 | — | — | US | disclosed |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-08-15 | — | — | US | disclosed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300951-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | USP2 4556/4885LMNA 4345/4885SLC6A4 4857/4885 |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | USP2 4556/4885LMNA 4345/4885SLC6A4 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.