SCHEMBL30901162

SCHEMBL30901162

O=C1CCNc2ccc(OCc3ccccc3)cc2N1

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 15/20 0.70
MAOA P21397 14/20 0.70
CREBBP Q92793 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29262890 1.00 MAOB (0.70) MAOBMAOACREBBP
SCHEMBL22368732 0.95 MAOB (0.70) MAOBMAOACREBBP
SCHEMBL31414465 0.82 MAOB (1.00) MAOBMAOACREBBP
SCHEMBL6721655 0.82 MAOB (1.00) MAOBMAOACREBBP
SCHEMBL2236580 0.82 MAOB (1.00) MAOBMAOACREBBP
SCHEMBL15413967 0.80 MAOB (0.85) MAOBMAOACREBBP
SCHEMBL3875255 0.80 MAOA (0.68) MAOBMAOA
SCHEMBL6294106 0.80 MAOB (0.61) MAOBMAOACREBBP
Hydrochloric Acid SCHEMBL3902331 0.79 MAOA (0.66) MAOBMAOA
SCHEMBL4717674 0.79 MAOB (0.66) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221679-A Benzo [ b ] [1,4] diazepine [4,5-e ] tetrazole derivative and pharmaceutically acceptable salt, preparation method and application thereof 常熟理工学院 2024-06-21 CN disclosed