Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377657 | 0.93 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL29641611 | 0.92 | DPP4 (0.55) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL30274201 | 0.90 | DPP4 (0.53) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL29575785 | 0.90 | DPP4 (0.53) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL17352470 | 0.89 | OPRM1 (0.46) | ACERENOPRM1XIAPF2 | |
| SCHEMBL29366371 | 0.89 | OPRM1 (0.46) | ACERENOPRM1XIAPF2 | |
| SCHEMBL29377214 | 0.88 | DPP4 (0.50) | DPP4ACERENOPRM1XIAP | |
| SCHEMBL29485136 | 0.88 | DPP4 (0.51) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL30473075 | 0.88 | DPP4 (0.51) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL29641763 | 0.88 | DPP4 (0.51) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12576160-B2 | Bispecific nanoparticle systems for targeting cancer cells | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2026-03-17 | — | — | US | disclosed |
| US-20240148899-A1 | BISPECIFIC NANOPARTICLE SYSTEMS FOR TARGETING CANCER CELLS | UNIVERSITY OF NOTRE DAME DU LAC | 2024-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12576160-B2 | Bispecific nanoparticle systems for targeting cancer cells | CD47, CD4, CD2 | DPP4 4497/4885FAP 1446/4885DPP8 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.