Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21979362 | 1.00 | HTT (0.36) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL29303426 | 0.86 | LMNA (0.33) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL31178973 | 0.86 | AXL (0.43) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL15995781 | 0.84 | KDM4E (0.34) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL22717640 | 0.84 | SCN9A (0.37) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL24525102 | 0.84 | F2RL1 (0.45) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL29654702 | 0.84 | F2RL1 (0.45) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL16722619 | 0.84 | F2RL1 (0.39) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL31156165 | 0.84 | SCN9A (0.37) | HTTMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL27227820 | 0.81 | HTT (0.44) | HTTHPGDALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |