Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 9/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 9/20 | 0.45 |
| ▸ | ITGAL | P20701 | 9/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21979078 | 1.00 | ITGB2 (0.45) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL21979080 | 1.00 | ITGB2 (0.45) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL21957148 | 0.94 | ITGB2 (0.45) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL31027342 | 0.94 | ITGB2 (0.45) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL21957149 | 0.94 | ITGB2 (0.45) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL30901281 | 0.91 | ITGA4 (0.47) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL21978759 | 0.91 | ITGA4 (0.47) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL21978757 | 0.91 | ITGA4 (0.47) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL23808055 | 0.88 | ITGB2 (0.38) | ITGB2ICAM1ITGALITGA4ITGB1 | |
| SCHEMBL29579892 | 0.88 | ITGB2 (0.38) | ITGB2ICAM1ITGALITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |