SCHEMBL30901419

SCHEMBL30901419

CN1CCC(N=CN2CCN(C)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
NCF1 P14598 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL934049 0.66
SCHEMBL19684329 0.66
SCHEMBL11917711 0.64
SCHEMBL17021251 0.64
SCHEMBL1749986 0.64 NCF1 (0.34) NCF1
SCHEMBL16488107 0.61
SCHEMBL15783069 0.61 NCF1 (0.41) NCF1
SCHEMBL22877041 0.61 NCF1 (0.36) NCF1
SCHEMBL18828781 0.61 NCF1 (0.36) NCF1
SCHEMBL23742267 0.59 NCF1 (0.43) NCF1MEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4357343-A1 RNA-BINDING MOLECULES WITH A SMALL CORE SCAFFOLD (R-SCORE) AND USES THEREOF Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-04-24 EP disclosed