Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | IDO1 | P14902 | 2/20 | 0.65 |
| ▸ | TDO2 | P48775 | 2/20 | 0.65 |
| ▸ | CASP6 | P55212 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973087 | 1.00 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11972798 | 0.85 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8724077 | 0.81 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL25253980 | 0.79 | MAPT (0.79) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27190082 | 0.79 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18496985 | 0.79 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2555260 | 0.78 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7960630 | 0.76 | MAPT (0.79) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10510901 | 0.76 | SLC40A1 (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24716165 | 0.76 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820225-A | 3- (8-amino-5, 6-difluoro-4-quinolyl) -2-cyanoacrylate, and preparation method and application thereof | 湘潭大学 | 2024-04-05 | — | — | CN | disclosed |