SCHEMBL30901465

SCHEMBL30901465

Clc1c2ccccc2c(-c2cccnc2)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 8/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP11B1 P15538 5/20 0.47
CYP11B2 P19099 5/20 0.46
CYP17A1 P05093 3/20 0.46
CYP19A1 P11511 3/20 0.46
IDO1 P14902 1/20 0.46
LRRK2 Q5S007 1/20 0.46
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TYMP P19971 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29242869 1.00 CYP2A6 (0.52) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL30901482 0.91 CYP2A6 (0.52) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL29242852 0.91 CYP2A6 (0.52) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL13145318 0.90 CYP2A6 (0.64) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL29515584 0.90 CYP2A6 (0.64) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL24662771 0.86 CYP2A6 (0.58) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL1102698 0.82 CYP2A6 (0.54) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL13911013 0.82 CYP2A6 (0.58) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL2813022 0.81 CYP2A6 (0.52) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL17996010 0.81 CYP11B2 (0.56) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117999268-A Organic compound and organic electroluminescent element using same 索路思高新材料有限公司 2024-05-07 CN disclosed