SCHEMBL30901466

SCHEMBL30901466

Clc1c2ccccc2c(-c2ccc(-c3ccccc3)nc2)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 2/20 0.45
LDHA P00338 1/20 0.42
CYP11B1 P15538 5/20 0.39
CYP11B2 P19099 5/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CHRNB2 P17787 2/20 0.38
CHRNA3 P32297 2/20 0.38
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
BAZ2B Q9UIF8 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29242850 1.00 HPGDS (0.45) HPGDSLDHACYP11B1CYP11B2MAOA
SCHEMBL12345155 0.91 HPGDS (0.51) HPGDSLDHACYP11B1CYP11B2CHRNB2
SCHEMBL29655386 0.91 HPGDS (0.51) HPGDSLDHACYP11B1CYP11B2CHRNB2
SCHEMBL12435755 0.89 HPGDS (0.50) HPGDSLDHACYP11B1CYP11B2CHRNB2
SCHEMBL29134690 0.88 CYP1A2 (0.45) HPGDSLDHACYP11B1CYP11B2MAOB
SCHEMBL30775115 0.88 CYP1A2 (0.45) HPGDSLDHACYP11B1CYP11B2MAOB
SCHEMBL12435999 0.87 HPGDS (0.49) HPGDSLDHACYP11B1CYP11B2CHRNB2
SCHEMBL12345194 0.85 HPGDS (0.50) HPGDSLDHACYP11B1CYP11B2CHRNB2
SCHEMBL28548915 0.83 HPGDS (0.45) HPGDSLDHACYP11B1CYP11B2CHRNB2
SCHEMBL29959399 0.83 HPGDS (0.45) HPGDSLDHACYP11B1CYP11B2CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117999268-A Organic compound and organic electroluminescent element using same 索路思高新材料有限公司 2024-05-07 CN disclosed