SCHEMBL309017

SCHEMBL309017

O=C(CO)c1cccc(Br)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.59
ALDH1A1 P00352 3/20 0.54
GLA P06280 1/20 0.54
TP53 P04637 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
HPGD P15428 1/20 0.49
C1S P09871 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 2/20 0.48
MGAM O43451 1/20 0.48
AMY1A P0DUB6 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
RXFP1 Q9HBX9 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30758864 0.85 PARP1 (0.61) PARP1ALDH1A1GLATP53L3MBTL1
SCHEMBL12235278 0.84 TDP1 (0.48) ALDH1A1L3MBTL1NPC1HPGDMEN1
SCHEMBL316026 0.83 GSK3B (0.59) PARP1ALDH1A1GLATP53L3MBTL1
SCHEMBL2203444 0.83 PARP1 (0.59) PARP1ALDH1A1GLATP53L3MBTL1
SCHEMBL6390040 0.82 ALDH1A1 (0.57) PARP1ALDH1A1GLATP53L3MBTL1
SCHEMBL244595 0.82 PARP1 (0.57) PARP1ALDH1A1GLATP53L3MBTL1
SCHEMBL1808868 0.82 PARP1 (0.62) PARP1ALDH1A1GLATP53L3MBTL1
SCHEMBL5546092 0.82 PARP1 (0.57) PARP1ALDH1A1GLATP53L3MBTL1
SCHEMBL6393460 0.82 GSK3B (0.59) PARP1ALDH1A1GLATP53L3MBTL1
SCHEMBL31149717 0.82 PARP1 (0.62) PARP1ALDH1A1GLATP53L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119606947-A Preparation method and application of chromone compound 广西民族大学 2025-03-14 CN claimed
CN-114573534-B Preparation method of 5-bromobenzofuranone 八叶草健康产业研究院(厦门)有限公司 2025-01-24 CN claimed
CN-117643584-A Preparation method of sulfachromone compound for candida albicans resistant medicine 广西民族大学 2024-03-05 CN claimed
CN-114751870-B 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof 贵州医科大学 2023-10-20 CN claimed
CN-114751870-A 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof 贵州医科大学 2022-07-15 CN claimed
CN-114573534-A Preparation method of 5-bromobenzofuranone 八叶草健康产业研究院(厦门)有限公司 2022-06-03 CN claimed
CN-113968882-A Optically pure (S) -2- (diphenylphosphine acyl) chromium-4-ketone and preparation method thereof 南京工业大学 2022-01-25 CN claimed
CN-109678788-B 1, 2-diaryl indole, derivative and synthetic method thereof 湘潭大学 2021-05-04 CN claimed
CN-109678788-A A kind of 1,2- diaryl indoles, derivative and its synthetic method 湘潭大学 2019-04-26 CN claimed
CN-108484511-A A kind of ligustrazine chalcone compounds and its preparation method and application 山东大学 2018-09-04 CN claimed
WO-2004058203-A2 AGENT FOR DYEING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (US) 2004-07-15 WO claimed
WO-2004058200-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-07-15 WO claimed
EP-1434557-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP claimed
EP-1432388-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
EP-1433469-A1 Composition for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
WO-2004022016-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-03-18 WO claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
WO-2003030847-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed