Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029618 | 1.00 | MAP4K4 (0.48) | MAP4K4CYP11B2MEN1KMT2ACNR1 | |
| SCHEMBL31029670 | 0.87 | MAP4K4 (0.62) | MAP4K4MEN1KMT2ACNR1CNR2 | |
| SCHEMBL30902260 | 0.87 | MAP4K4 (0.62) | MAP4K4MEN1KMT2ACNR1CNR2 | |
| SCHEMBL30902102 | 0.79 | HTT (0.52) | MAP4K4CYP11B2KITSCD5JAK3 | |
| SCHEMBL31029554 | 0.79 | HTT (0.52) | MAP4K4CYP11B2KITSCD5JAK3 | |
| SCHEMBL31029707 | 0.78 | JAK1 (0.46) | MAP4K4MEN1KMT2AJAK3 | |
| SCHEMBL30902198 | 0.78 | JAK1 (0.46) | MAP4K4MEN1KMT2AJAK3 | |
| SCHEMBL30902192 | 0.77 | MAP4K4 (0.48) | MAP4K4MEN1KMT2ACNR1CNR2 | |
| SCHEMBL31029643 | 0.77 | MAP4K4 (0.48) | MAP4K4MEN1KMT2ACNR1CNR2 | |
| SCHEMBL31727752 | 0.77 | CYP11B2 (0.49) | CYP11B2MEN1KMT2AACACBEIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |