Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16533429 | 0.88 | HSP90AB1 (0.58) | HSP90AB1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL31274783 | 0.86 | HSP90AB1 (0.46) | HSP90AB1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15317599 | 0.82 | ALDH1A1 (0.43) | HSP90AB1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL2541070 | 0.78 | RECQL (0.41) | HSP90AB1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5897930 | 0.78 | SMN1; SMN2 (0.37) | HSP90AB1ALDH1A1RAB9AKDM4ETAS1R3 | |
| SCHEMBL29879916 | 0.78 | RECQL (0.41) | HSP90AB1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL24094576 | 0.77 | HSP90AB1 (0.46) | HSP90AB1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17169789 | 0.77 | SMN1; SMN2 (0.38) | HSP90AB1ALDH1A1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL30903033 | 0.76 | HSP90AB1 (0.45) | HSP90AB1ALDH1A1NPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL7451596 | 0.75 | SMN1; SMN2 (0.38) | HSP90AB1ALDH1A1RAB9AKDM4ETAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105563-A1 | SUBSTITUTED BICYCLIC PYRIDONE DERIVATIVES | PFIZER INC. (US) | 2024-05-23 | — | — | WO | disclosed |