SCHEMBL30903269

CSCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)C(C)C)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	3/20	0.53

▸	GLP1R	P43220	4/20	0.50

▸	GCGR	P47871	1/20	0.50

▸	GIPR	P48546	1/20	0.50

▸	OPRM1	P35372	2/20	0.49

▸	OPRD1	P41143	2/20	0.49

▸	TFPI	P10646	1/20	0.49

▸	BACE1	P56817	1/20	0.48

▸	BACE2	Q9Y5Z0	1/20	0.48

▸	OPRK1	P41145	1/20	0.48

▸	CALCR	P30988	3/20	0.47

▸	CCKBR	P32239	1/20	0.47

▸	VIPR2	P41587	1/20	0.46

▸	KEAP1	Q14145	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29461526	0.96	IL23R (0.53)	IL23RGLP1RGCGRGIPROPRM1
SCHEMBL30903271	0.93	IL23R (0.53)	IL23RGLP1RGCGRGIPROPRM1
SCHEMBL29811053	0.90	IL23R (0.59)	IL23RGLP1RGCGRGIPROPRM1
SCHEMBL30733315	0.89	BACE1 (0.56)	OPRM1OPRD1BACE1BACE2VIPR2
SCHEMBL29649202	0.87	IL23R (0.60)	IL23RGLP1RGCGRGIPRTFPI
SCHEMBL31688316	0.86	GLP1R (0.56)	GLP1RGCGRGIPRTFPIBACE1
SCHEMBL30618464	0.86	IL23R (0.50)	IL23RGLP1RGCGRGIPROPRM1
SCHEMBL29723863	0.85	NPY1R (0.50)	IL23ROPRM1OPRD1OPRK1CCKBR
SCHEMBL30567730	0.85	TFPI (0.66)	IL23RGLP1RGCGRGIPROPRM1
SCHEMBL10428706	0.85	IL23R (0.54)	IL23RGLP1RGCGRGIPRTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240148849-A1	IMMUNOGENIC COMPOSITION, USE AND METHODS	GLAXOSMITHKLINE BIOLOGICALS SA (BE)	2024-05-09	—	—	US	disclosed