SCHEMBL29811053

SCHEMBL29811053

CSCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 3/20 0.59
▸ TFPI P10646 1/20 0.56
▸ GLP1R P43220 3/20 0.56
▸ GCGR P47871 1/20 0.56
▸ GIPR P48546 1/20 0.56
▸ VIPR2 P41587 2/20 0.55
▸ KEAP1 Q14145 1/20 0.54
▸ CALCR P30988 3/20 0.54
▸ VIPR1 P32241 2/20 0.54
▸ OPRM1 P35372 1/20 0.53
▸ OPRD1 P41143 1/20 0.53
▸ OPRK1 P41145 1/20 0.53
▸ BACE1 P56817 1/20 0.53
▸ BACE2 Q9Y5Z0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30903271 0.93 IL23R (0.53) IL23RTFPIGLP1RGCGRGIPR
SCHEMBL29609357 0.92 TFPI (0.64) IL23RTFPIGLP1RGCGRGIPR
SCHEMBL31182935 0.92 TFPI (0.62) IL23RTFPIGLP1RGCGRGIPR
SCHEMBL31182918 0.91 TFPI (0.64) IL23RTFPIGLP1RGCGRGIPR
SCHEMBL29811062 0.90 IL23R (0.59) IL23RTFPIGLP1RGCGRGIPR
SCHEMBL30903269 0.90 IL23R (0.53) IL23RTFPIGLP1RGCGRGIPR
SCHEMBL29696462 0.90 OPRM1 (0.60) IL23RTFPIKEAP1OPRM1OPRD1
SCHEMBL29649226 0.90 VIPR2 (0.60) TFPIGLP1RVIPR2CALCRVIPR1
SCHEMBL29836442 0.89 TFPI (0.55) IL23RTFPIGLP1RVIPR2OPRM1
SCHEMBL29461526 0.89 IL23R (0.53) IL23RTFPIGLP1RGCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 — — US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 — — US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 IL23R 1762/4885TFPI 1391/4885GLP1R 2107/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 IL23R 1762/4885TFPI 1391/4885GLP1R 2107/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 IL23R 520/4885TFPI 3568/4885GLP1R 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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