Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30904779 | 0.87 | MEN1 (0.59) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL29206795 | 0.85 | KMT2A (0.55) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL30904790 | 0.84 | KDM4E (0.56) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL30904788 | 0.80 | MEN1 (0.51) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL23994321 | 0.76 | MEN1 (0.54) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL31065716 | 0.76 | MEN1 (1.00) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL23995083 | 0.71 | KDM4E (0.47) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL23995088 | 0.68 | MAPT (0.46) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL23995086 | 0.68 | KDM4E (0.46) | MEN1KMT2ATAAR1KDM4EMAPT | |
| SCHEMBL23995372 | 0.68 | MEN1 (0.43) | MEN1KMT2ATAAR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |