Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 4/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30904788 | 0.85 | MEN1 (0.51) | KDM4EMEN1MAPTKMT2ATAAR1 | |
| SCHEMBL30904785 | 0.84 | MEN1 (0.59) | KDM4EMEN1MAPTKMT2ATAAR1 | |
| SCHEMBL30904779 | 0.84 | MEN1 (0.59) | KDM4EMEN1MAPTKMT2ATAAR1 | |
| SCHEMBL29206795 | 0.81 | KMT2A (0.55) | KDM4EMEN1MAPTKMT2ATAAR1 | |
| SCHEMBL23994321 | 0.74 | MEN1 (0.54) | KDM4EMEN1MAPTKMT2ATAAR1 | |
| SCHEMBL30904777 | 0.74 | ACP1 (0.46) | KDM4EMEN1MAPTKMT2AACP1 | |
| SCHEMBL29206815 | 0.74 | ACP1 (0.46) | KDM4EMEN1MAPTKMT2AACP1 | |
| SCHEMBL31065716 | 0.73 | MEN1 (1.00) | KDM4EMEN1MAPTKMT2ATAAR1 | |
| SCHEMBL29206797 | 0.71 | ACP1 (0.44) | KDM4EMEN1MAPTKMT2AACP1 | |
| SCHEMBL24300541 | 0.71 | NT5E (0.50) | KDM4ENT5EPDCD1CD274ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |