Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27227094 | 1.00 | AAK1 (0.43) | AAK1DRD2PARP1PARP2SIGMAR1 | |
| SCHEMBL27227030 | 0.88 | PRKAA2 (0.46) | AAK1PARP1PARP2SIGMAR1AKT1 | |
| SCHEMBL30905662 | 0.88 | PRKAA2 (0.46) | AAK1PARP1PARP2SIGMAR1AKT1 | |
| SCHEMBL30802282 | 0.87 | SIGMAR1 (0.48) | DRD2SIGMAR1MAPK1PRKAA2DRD4 | |
| SCHEMBL30802459 | 0.86 | AKT1 (0.49) | AAK1DRD2PARP1PARP2SIGMAR1 | |
| SCHEMBL29324395 | 0.86 | AKT1 (0.49) | AAK1DRD2PARP1PARP2SIGMAR1 | |
| SCHEMBL30802301 | 0.85 | MAPT (0.43) | POLBMAPTMAPK1 | |
| SCHEMBL27226398 | 0.85 | MAPT (0.43) | POLBMAPTMAPK1 | |
| SCHEMBL27227414 | 0.83 | SIGMAR1 (0.44) | AAK1DRD2PARP1PARP2SIGMAR1 | |
| SCHEMBL2173703 | 0.80 | IGF1R (0.47) | POLBMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107565-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |