Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 5/20 | 0.38 |
| ▸ | ACE | P12821 | 4/20 | 0.38 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571920 | 0.90 | PTGS1 (0.59) | PTGS1GSTK1GLO1 | |
| SCHEMBL29637953 | 0.90 | PTGS1 (0.64) | PTGS1GSTK1ALDH1A1MAPTLMNA | |
| SCHEMBL30905702 | 0.89 | PTGS1 (0.64) | PTGS1GSTK1ALDH1A1MAPTLMNA | |
| SCHEMBL29671002 | 0.88 | PTGS1 (0.47) | PTGS1GSTK1ALDH1A1MAPTLMNA | |
| SCHEMBL30661089 | 0.87 | PTGS1 (0.61) | PTGS1GSTK1ALDH1A1MAPTLMNA | |
| SCHEMBL29538762 | 0.87 | PTGS1 (0.54) | PTGS1GSTK1ALDH1A1MAPTLMNA | |
| SCHEMBL29671487 | 0.87 | PTGS1 (0.46) | PTGS1GSTK1ALDH1A1MAPTLMNA | |
| SCHEMBL29499687 | 0.87 | PTGS1 (0.46) | PTGS1GSTK1ALDH1A1MAPTLMNA | |
| SCHEMBL30037966 | 0.85 | PTGS1 (0.44) | PTGS1GSTK1ALDH1A1MAPTLMNA | |
| SCHEMBL209654 | 0.84 | PTGS1 (0.70) | PTGS1GSTK1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206802-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-06-26 | — | — | US | disclosed |
| US-20240117006-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240117006-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | ITGA2B, ITGB1, ITGA1 | PTGS1 3990/4885GSTK1 3112/4885ALDH1A1 2700/4885 |
| US-20250206802-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | ITGA2B, ITGB1, ITGA1 | PTGS1 3990/4885GSTK1 3112/4885ALDH1A1 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.