Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 11/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCND2 | P30279 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25141804 | 1.00 | DDB1 (0.53) | DDB1CRBNCDK4CCND1CCND2 | |
| SCHEMBL25141584 | 0.93 | DDB1 (0.53) | DDB1CRBNCDK4CCND1CCND2 | |
| SCHEMBL27397706 | 0.92 | DDB1 (0.44) | DDB1CRBNCDK4CCND1CCND2 | |
| SCHEMBL26255871 | 0.85 | CRBN (0.48) | DDB1CRBN | |
| SCHEMBL32670490 | 0.85 | CRBN (0.48) | DDB1CRBN | |
| SCHEMBL30905936 | 0.85 | CRBN (0.49) | DDB1CRBN | |
| SCHEMBL30905891 | 0.85 | DDB1 (0.53) | DDB1CRBNCDK4CCND1CCND2 | |
| SCHEMBL30905816 | 0.85 | DDB1 (0.53) | DDB1CRBNCDK4CCND1CCND2 | |
| SCHEMBL25141607 | 0.84 | CRBN (0.52) | DDB1CRBNMAPTPDK2SMN1; SMN2 | |
| SCHEMBL25141689 | 0.84 | DDB1 (0.52) | DDB1CRBNMAPTPDK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112119-A1 | DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112120-A1 | DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112122-A1 | DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |