SCHEMBL27397706 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	DDB1	Q16531	6/20	0.44

▸	CRBN	Q96SW2	6/20	0.44

▸	ALK	Q9UM73	5/20	0.41

▸	CDK4	P11802	1/20	0.40

▸	CCND1	P24385	1/20	0.40

▸	CCND2	P30279	1/20	0.40

▸	CCND3	P30281	1/20	0.40

▸	MAPT	P10636	4/20	0.40

▸	MEN1	O00255	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	KMT2A	Q03164	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	PDK2	Q15119	1/20	0.39

▸	ALDH1A1	P00352	1/20	0.38

▸	LMNA	P02545	1/20	0.38

▸	GPR119	Q8TDV5	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30905908	0.92	DDB1 (0.53)	DDB1CRBNALKCDK4CCND1
SCHEMBL25141804	0.92	DDB1 (0.53)	DDB1CRBNALKCDK4CCND1
SCHEMBL25141584	0.85	DDB1 (0.53)	DDB1CRBNALKCDK4CCND1
SCHEMBL24861331	0.81	CRBN (0.41)	DDB1CRBNCDK4CCND1CCND2
SCHEMBL27415348	0.79	DDB1 (0.44)	DDB1CRBNALKCDK4CCND1
SCHEMBL21982902	0.78	CRBN (0.54)	DDB1CRBNMAPTPDK2ALDH1A1
SCHEMBL32670490	0.77	CRBN (0.48)	DDB1CRBN
SCHEMBL26255871	0.77	CRBN (0.48)	DDB1CRBN
SCHEMBL25141670	0.77	CRBN (0.35)	DDB1CRBN
SCHEMBL30905816	0.77	DDB1 (0.53)	DDB1CRBNCDK4CCND1CCND2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024112120-A1	DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME	주식회사 이노큐어테라퓨틱스	2024-05-30	—	—	WO	disclosed