Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217002 | 0.74 | MAOA (0.45) | LMNAMAOAMAOBRAB9AKMT2A | |
| SCHEMBL295051 | 0.73 | MAOA (0.43) | LMNAMAOAMAOBRAB9A | |
| SCHEMBL3626527 | 0.73 | MAOA (0.43) | LMNAMAOAMAOBRAB9A | |
| SCHEMBL4206535 | 0.73 | MAOA (0.43) | LMNAMAOAMAOBRAB9A | |
| SCHEMBL9935109 | 0.73 | MAOA (0.43) | LMNAMAOAMAOBRAB9A | |
| SCHEMBL2071142 | 0.72 | MAOA (0.39) | LMNAALDH1A1MAOAMAOBKDM4E | |
| SCHEMBL9773035 | 0.70 | MAOA (0.41) | LMNAMAOAMAOBRAB9A | |
| SCHEMBL10574211 | 0.70 | MAOA (0.41) | ALDH1A1MAOAMAOBRAB9AKDM4E | |
| SCHEMBL10645704 | 0.70 | MAOA (0.41) | LMNAALDH1A1MAOAMAOBRAB9A | |
| SCHEMBL295013 | 0.70 | MAOA (0.41) | LMNAMAOAMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981929-B2 | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells | JANSSEN BIOTECH, INC. (US) | 2024-05-14 | — | — | US | disclosed |