Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964970 | 0.85 | NR1H2 (0.44) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL25933195 | 0.84 | NR1H2 (0.44) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL30493388 | 0.84 | NR1H2 (0.44) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL30906308 | 0.84 | RET (0.46) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL25933193 | 0.84 | NR1H2 (0.44) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL27263543 | 0.83 | GPR119 (0.44) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL30493266 | 0.83 | NR1H2 (0.43) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL25933234 | 0.83 | NR1H2 (0.43) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL22790061 | 0.80 | NR4A2 (0.41) | NR1H2NR1H3GPR119HSD11B1HDAC1 | |
| SCHEMBL22790337 | 0.80 | NR4A2 (0.41) | NR1H2NR1H3GPR119HSD11B1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |