Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.44 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.44 |
| ▸ | WIZ | O95785 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25576779 | 1.00 | CRBN (0.49) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL30741731 | 0.93 | CRBN (0.50) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL20234420 | 0.90 | CRBN (0.49) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL30906309 | 0.90 | IKZF2 (0.51) | CRBNIKZF2 | |
| SCHEMBL25576872 | 0.89 | CRBN (0.49) | CRBNIKZF2IKZF1 | |
| SCHEMBL30906303 | 0.89 | CRBN (0.49) | CRBNIKZF2IKZF1 | |
| SCHEMBL20231475 | 0.88 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL30906267 | 0.88 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL30906235 | 0.88 | CRBN (0.48) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL21759799 | 0.85 | CRBN (0.53) | CRBNIKZF2CSNK1A1DDB1GSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024162746-A1 | INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF | 한국화학연구원 | 2024-08-08 | — | — | WO | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |