SCHEMBL30906309

SCHEMBL30906309

CC(C)(C)OC(=O)N1CCC(CN2CCN(CC#Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 3/20 0.51
▸ BTK Q06187 15/20 0.45
▸ CRBN Q96SW2 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25576872 0.94 CRBN (0.49) IKZF2BTKCRBN
SCHEMBL30906303 0.94 CRBN (0.49) IKZF2BTKCRBN
SCHEMBL30906224 0.90 CRBN (0.49) IKZF2CRBN
SCHEMBL25576779 0.90 CRBN (0.49) IKZF2CRBN
SCHEMBL30906227 0.87 CRBN (0.50) BTKCRBN
SCHEMBL30906235 0.87 CRBN (0.48) IKZF2BTKCRBN
SCHEMBL31129522 0.86 CRBN (0.57) IKZF2CRBN
SCHEMBL22581062 0.86 CRBN (0.57) IKZF2CRBN
SCHEMBL20234420 0.86 CRBN (0.49) IKZF2CRBN
SCHEMBL30942356 0.86 CRBN (0.57) IKZF2CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598905-A2 CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS University of Florida Research Foundation, Incorporated (US) 2025-08-13 — — EP disclosed
WO-2024077023-A2 CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-04-11 — — WO disclosed
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