Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.54 |
| ▸ | ESR1 | P03372 | 10/20 | 0.54 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24734974 | 0.95 | CRBN (0.51) | CRBNESR1IKZF2IKZF1 | |
| SCHEMBL29841236 | 0.93 | CRBN (0.52) | CRBNESR1IKZF2IKZF1 | |
| SCHEMBL30822432 | 0.93 | CRBN (0.52) | CRBNESR1IKZF2IKZF1 | |
| SCHEMBL24734992 | 0.93 | CRBN (0.52) | CRBNESR1IKZF2IKZF1 | |
| SCHEMBL30906292 | 0.92 | CRBN (0.57) | CRBNESR1IKZF2ARIKZF1 | |
| SCHEMBL30822421 | 0.92 | CRBN (0.53) | CRBNESR1IKZF2IKZF1 | |
| SCHEMBL25373583 | 0.89 | CRBN (0.50) | CRBNESR1IKZF2IKZF1 | |
| SCHEMBL30906261 | 0.89 | CRBN (0.60) | CRBNESR1IKZF2IKZF1 | |
| SCHEMBL30906233 | 0.88 | CRBN (0.56) | CRBNESR1IKZF2ARIKZF1 | |
| SCHEMBL30906245 | 0.88 | ESR1 (0.53) | CRBNESR1IKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598905-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | University of Florida Research Foundation, Incorporated (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077023-A2 | CEREBLON-RECRUITING BCL-XL/BCL-2 DUAL DEGRADERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-11 | — | — | WO | disclosed |