Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FRK | P42685 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105041 | 0.83 | CSNK1D (0.57) | CSNK1DMAP4K4MAPK9CSNK1A1GSK3B | |
| SCHEMBL3110918 | 0.81 | THRB (0.54) | THRBTGFBR1CSNK1DMAPK14 | |
| SCHEMBL3099814 | 0.77 | CSNK1D (0.38) | THRBTGFBR1CSNK1DGRM5MAP4K4 | |
| SCHEMBL3102476 | 0.76 | CSNK1D (0.38) | THRBTGFBR1CSNK1DGSK3BMAPK14 | |
| SCHEMBL3107978 | 0.73 | CSNK1D (0.42) | THRBTGFBR1CSNK1DMAP4K4MAPK9 | |
| SCHEMBL10290857 | 0.73 | THRB (0.56) | THRBTGFBR1CSNK1DMAPK14 | |
| SCHEMBL10290856 | 0.72 | CSNK1D (0.54) | THRBTGFBR1CSNK1DGSK3BMAPK14 | |
| SCHEMBL10290371 | 0.70 | THRB (0.52) | THRBTGFBR1CSNK1DMAPK14 | |
| SCHEMBL3105536 | 0.70 | CSNK1D (0.53) | CSNK1DMAP4K4MAPK9CSNK1A1GSK3B | |
| SCHEMBL10290860 | 0.69 | CSNK1D (0.52) | THRBTGFBR1CSNK1DGSK3BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217600-B1 | FUNGICIDAL BICYCLIC PYRAZOLES | DU PONT (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8288375-B2 | Fungicidal bicyclic pyrazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-16 | — | — | US | disclosed |
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | CYP1B1, CBR1, CYP1A1 | THRB 4120/4885TGFBR1 1459/4885CSNK1D 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.