SCHEMBL30906930

SCHEMBL30906930

CCC(C)c1c([N+](=O)[O-])ccc(O)c1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 4/20 0.45
CTSB P07858 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
HPGD P15428 3/20 0.40
TSHR P16473 3/20 0.40
CYP3A4 P08684 2/20 0.40
TP53 P04637 2/20 0.40
HIF1A Q16665 1/20 0.40
CTSH P09668 1/20 0.40
ALOX12 P18054 2/20 0.40
ALOX15 P16050 2/20 0.40
MAPT P10636 2/20 0.39
CASP6 P55212 2/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
ALDH1A1 P00352 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1812870 1.00 GPR35 (0.45) GPR35CTSBSMN1; SMN2HPGDTSHR
SCHEMBL29967588 0.88 GPR35 (0.45) GPR35CTSBSMN1; SMN2HPGDTSHR
SCHEMBL1938445 0.88 GPR35 (0.45) GPR35CTSBSMN1; SMN2HPGDTSHR
SCHEMBL11686194 0.79 GPR35 (0.50) GPR35SMN1; SMN2TSHRALOX12ALOX15
SCHEMBL30679179 0.78 TDP1 (0.43) GPR35HPGDTSHRCYP3A4ALOX12
SCHEMBL2012619 0.78 TDP1 (0.43) GPR35HPGDTSHRCYP3A4ALOX12
SCHEMBL6905228 0.78 TSHR (0.46) GPR35SMN1; SMN2HPGDTSHRALOX12
SCHEMBL16225013 0.76 TDP1 (0.50) GPR35SMN1; SMN2TSHRCYP3A4MAPT
SCHEMBL11717704 0.76 GPR35 (0.42) GPR35CTSBSMN1; SMN2HPGDTSHR
SCHEMBL1938443 0.75 TDP1 (0.43) GPR35HPGDTSHRCYP3A4ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084673-A Method for preparing 2, 4-dinitro-6-sec-butylphenol by micro-channel equipment 吉林省九新实业集团化工有限公司 2024-05-28 CN disclosed
CN-118084673-A Method for preparing 2, 4-dinitro-6-sec-butylphenol by micro-channel equipment 吉林省九新实业集团化工有限公司 2024-05-28 CN disclosed