Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.32 |
| ▸ | CCR9 | P51686 | 2/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592339 | 0.84 | GRM5 (0.36) | PAX8GRM5P2RX3KAT6AKAT5 | |
| SCHEMBL30907180 | 0.83 | SYK (0.34) | P2RX3STK17BSTK17ACKS1BSKP1 | |
| SCHEMBL30907219 | 0.83 | PAX8 (0.42) | TTKPAX8GRM5P2RX3CCR9 | |
| SCHEMBL16978804 | 0.82 | TTK (0.53) | TTKPAX8SYKAAK1 | |
| SCHEMBL3633134 | 0.82 | PAX8 (0.43) | TTKPAX8CKS1BSKP1SKP2 | |
| SCHEMBL23535828 | 0.79 | KDM4E (0.41) | TTKPAX8GPBAR1 | |
| SCHEMBL31504563 | 0.79 | KDM4E (0.41) | TTKPAX8GPBAR1 | |
| SCHEMBL31649564 | 0.78 | TTK (0.35) | TTKPAX8 | |
| SCHEMBL30041261 | 0.78 | TTK (0.37) | TTKPAX8USP30 | |
| SCHEMBL23535704 | 0.78 | TTK (0.37) | TTKPAX8USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |