SCHEMBL30907199

SCHEMBL30907199

CCCC(=O)c1ncc(-c2cc3cnc(NC(=O)C4CC4)cc3cn2)c(C)n1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 19/20 0.58
MAP4K1 Q92918 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30907457 0.84 ABL1 (0.61) ABL1MAP4K1
SCHEMBL30907290 0.83 ABL1 (0.53) ABL1
SCHEMBL30907506 0.81 ABL1 (0.61) ABL1
SCHEMBL30885011 0.80 ABL1 (0.42) ABL1
SCHEMBL30907263 0.80 ABL1 (0.56) ABL1
SCHEMBL30907565 0.80 ABL1 (0.56) ABL1
SCHEMBL30907269 0.80 ABL1 (0.56) ABL1
SCHEMBL30907339 0.78 ABL1 (0.65) ABL1MAP4K1
SCHEMBL30907456 0.77 ABL1 (0.53) ABL1
SCHEMBL30907604 0.76 ABL1 (0.61) ABL1MAP4K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024097953-A1 NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES ENLIVEN INC. (US) 2024-05-10 WO disclosed