SCHEMBL30907290

SCHEMBL30907290

CCCC(=O)c1ncc(-c2cnc3cc(NC(=O)C4CC4)ncc3c2)c(C)n1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30907199 0.83 ABL1 (0.58) ABL1
SCHEMBL30907133 0.81 ABL1 (0.52) ABL1
SCHEMBL30907581 0.81 ABL1 (0.52) ABL1
SCHEMBL30907381 0.79 ABL1 (0.32) ABL1
SCHEMBL30907301 0.79 ABL1 (0.60) ABL1
SCHEMBL30885011 0.78 ABL1 (0.42) ABL1
SCHEMBL30907444 0.75 ABL1 (0.76) ABL1
SCHEMBL30907281 0.75 ABL1 (0.76) ABL1
SCHEMBL30907455 0.75 ABL1 (0.76) ABL1
SCHEMBL30907111 0.73 ABL1 (0.43) ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024097953-A1 NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES ENLIVEN INC. (US) 2024-05-10 WO disclosed