Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.32 |
| ▸ | CCNK | O75909 | 2/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK7 | P50613 | 2/20 | 0.31 |
| ▸ | CCNH | P51946 | 2/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907434 | 0.92 | HTR2C (0.37) | RAB9ANPC1ABL1TP53HPGD | |
| SCHEMBL30907166 | 0.85 | ABL1 (0.34) | ABL1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30907611 | 0.82 | ABL1 (0.43) | ABL1 | |
| SCHEMBL30907412 | 0.82 | GPBAR1 (0.32) | ABL1 | |
| SCHEMBL30907430 | 0.82 | ABL1 (0.34) | ABL1KDM4EALDH1A1 | |
| SCHEMBL30907485 | 0.80 | MTOR (0.39) | RAB9ANPC1ABL1CDK2KDM4E | |
| SCHEMBL30907369 | 0.80 | ABL1 (0.33) | ABL1 | |
| SCHEMBL30907424 | 0.75 | ABL1 (0.42) | ABL1 | |
| SCHEMBL30907125 | 0.75 | ABL1 (0.42) | ABL1 | |
| SCHEMBL30907507 | 0.72 | PDE4B (0.38) | PDE4BPDE4DPDE4APDE4CABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |