Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907430 | 0.88 | ABL1 (0.34) | ABL1ALDH1A1 | |
| SCHEMBL30907412 | 0.88 | GPBAR1 (0.32) | ABL1 | |
| SCHEMBL30907369 | 0.86 | ABL1 (0.33) | ABL1 | |
| SCHEMBL30907259 | 0.85 | PDE4B (0.35) | ABL1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30907434 | 0.82 | HTR2C (0.37) | ABL1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL30907424 | 0.81 | ABL1 (0.42) | ABL1 | |
| SCHEMBL30907125 | 0.81 | ABL1 (0.42) | ABL1 | |
| SCHEMBL30907390 | 0.80 | BTK (0.34) | ABL1 | |
| SCHEMBL30907414 | 0.79 | GABRA1 (0.36) | ABL1 | |
| SCHEMBL30907139 | 0.78 | FGFR1 (0.39) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |