Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907447 | 1.00 | ABL1 (0.47) | ABL1MAP4K1ADORA2AADORA2B | |
| SCHEMBL30907181 | 1.00 | ABL1 (0.47) | ABL1MAP4K1ADORA2AADORA2B | |
| SCHEMBL30907421 | 0.88 | ABL1 (0.41) | ABL1MAP4K1ADORA2AADORA2B | |
| SCHEMBL30907231 | 0.83 | ABL1 (0.53) | ABL1MAP4K1 | |
| SCHEMBL30907238 | 0.83 | ABL1 (0.53) | ABL1MAP4K1 | |
| SCHEMBL30907473 | 0.83 | ABL1 (0.53) | ABL1MAP4K1 | |
| SCHEMBL30907392 | 0.82 | ABL1 (0.51) | ABL1MAP4K1 | |
| SCHEMBL30907630 | 0.82 | ABL1 (0.51) | ABL1MAP4K1 | |
| SCHEMBL30907282 | 0.82 | ABL1 (0.51) | ABL1MAP4K1 | |
| SCHEMBL30907257 | 0.81 | ABL1 (0.51) | ABL1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |