Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907447 | 0.88 | ABL1 (0.47) | ABL1MAP4K1ADORA2AADORA2B | |
| SCHEMBL30907181 | 0.88 | ABL1 (0.47) | ABL1MAP4K1ADORA2AADORA2B | |
| SCHEMBL30907341 | 0.88 | ABL1 (0.47) | ABL1MAP4K1ADORA2AADORA2B | |
| SCHEMBL30907368 | 0.83 | MAP4K1 (0.45) | ABL1MAP4K1 | |
| SCHEMBL30907084 | 0.83 | GSK3B (0.36) | ABL1MAP4K1ADORA2AADORA2BBTK | |
| SCHEMBL30907609 | 0.81 | ABL1 (0.43) | ABL1MAP4K1 | |
| SCHEMBL30907425 | 0.81 | ABL1 (0.46) | ABL1MAP4K1 | |
| SCHEMBL30907153 | 0.80 | ABL1 (0.52) | ABL1MAP4K1 | |
| SCHEMBL30907322 | 0.80 | FGFR1 (0.38) | KITBTK | |
| SCHEMBL30907390 | 0.80 | BTK (0.34) | ABL1KITBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |