Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907624 | 0.91 | GABRA1 (0.35) | ABL1MAP4K1HTT | |
| SCHEMBL30907314 | 0.83 | ABL1 (0.39) | ABL1MAP4K1 | |
| SCHEMBL30907560 | 0.82 | ABL1 (0.45) | ABL1MAP4K1HTT | |
| SCHEMBL30907248 | 0.78 | ABL1 (0.39) | ABL1MAP4K1 | |
| SCHEMBL30907267 | 0.78 | ABL1 (0.36) | ABL1MAP4K1 | |
| SCHEMBL30907127 | 0.77 | ABL1 (0.48) | ABL1MAP4K1 | |
| SCHEMBL30907640 | 0.76 | ABL1 (0.38) | ABL1 | |
| SCHEMBL30907099 | 0.76 | ABL1 (0.35) | ABL1MAP4K1 | |
| SCHEMBL30907616 | 0.74 | ABL1 (0.50) | ABL1 | |
| SCHEMBL30907615 | 0.74 | GABRA1 (0.38) | ABL1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |