Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13394489 | 0.84 | KMT2A (0.56) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL22237929 | 0.81 | KMT2A (0.53) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL21682115 | 0.79 | BACE1 (0.42) | KMT2ANPSR1ALDH1A1PABPC1CYP1A2 | |
| SCHEMBL31123833 | 0.79 | BACE1 (0.42) | KMT2ANPSR1ALDH1A1PABPC1CYP1A2 | |
| SCHEMBL30908292 | 0.77 | KMT2A (0.59) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL2178320 | 0.77 | EGFR (0.53) | KMT2AALDH1A1KDM4EMAPTGAA | |
| SCHEMBL3835940 | 0.76 | KMT2A (0.62) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL22509749 | 0.76 | KMT2A (0.62) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL22509835 | 0.73 | KMT2A (0.59) | KMT2ANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL19243071 | 0.70 | KMT2A (0.75) | KMT2ANPSR1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |