Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | NCK1 | P16333 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835603 | 0.83 | CYP1A2 (0.50) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL8302695 | 0.83 | POLB (0.48) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL22509749 | 0.83 | KMT2A (0.62) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL12970077 | 0.80 | KMT2A (0.42) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL22509835 | 0.80 | KMT2A (0.59) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL29911266 | 0.80 | BACE1 (0.46) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL3614209 | 0.80 | BACE1 (0.46) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL30908292 | 0.80 | KMT2A (0.59) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL862486 | 0.78 | ALDH1A1 (0.56) | KMT2ANPSR1ALDH1A1CYP1A2KDM4E | |
| SCHEMBL6033527 | 0.77 | ALDH1A1 (0.64) | KMT2AALDH1A1CYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751897-B1 | Derivatives of Bodipy | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| WO-2017139689-A1 | DERIVATIVES OF BODIPY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-08-17 | — | — | WO | disclosed |
| US-20170233414-A1 | DERIVATIVES OF BODIPY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-08-17 | — | — | US | disclosed |
| EP-2064180-B1 | 4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | MERCK SHARP & DOHME (US) | 2016-07-13 | — | — | EP | disclosed |
| US-9023489-B2 | Red phosphorescent compounds and organic electroluminescent devices using the same | LG DISPLAY CO., LTD. (KR) | 2015-05-05 | — | — | US | disclosed |
| US-9023489-B2 | Red phosphorescent compounds and organic electroluminescent devices using the same | LG DISPLAY CO., LTD. (KR) | 2015-05-05 | — | — | US | disclosed |
| US-9023489-B2 | Red phosphorescent compounds and organic electroluminescent devices using the same | LG DISPLAY CO., LTD. (KR) | 2015-05-05 | — | — | US | disclosed |
| US-8557848-B2 | 4,5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections | MERCK SHARP & DOHME CORP. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20100098661-A1 | 4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | SCHERING CORPORATION | 2010-04-22 | — | — | US | disclosed |
| EP-1783132-B1 | Red phosphorescent compounds and organic electromuninescent devices using the same | LG DISPLAY CO LTD (KR) | 2009-10-14 | — | — | EP | disclosed |
| US-20070104980-A1 | Red phosphorescent compounds and organic electroluminescent devices using the same | LG DISPLAY CO., LTD. (KR) | 2007-05-10 | — | — | US | disclosed |
| US-20070104980-A1 | Red phosphorescent compounds and organic electroluminescent devices using the same | LG DISPLAY CO., LTD. (KR) | 2007-05-10 | — | — | US | disclosed |
| US-20070104980-A1 | Red phosphorescent compounds and organic electroluminescent devices using the same | LG DISPLAY CO., LTD. (KR) | 2007-05-10 | — | — | US | disclosed |
| EP-1783132-A1 | Red phosphorescent compounds and organic electromuninescent devices using the same | LG Electronics Inc. (KR) | 2007-05-09 | — | — | EP | disclosed |
| EP-1783132-A1 | Red phosphorescent compounds and organic electromuninescent devices using the same | LG Electronics Inc. (KR) | 2007-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233414-A1 | DERIVATIVES OF BODIPY | NPC1L1, NPC1, ABCB4 | KMT2A 4438/4885NPSR1 3763/4885ALDH1A1 2043/4885 |
| US-20100098661-A1 | 4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | ZC3HAV1, IDO1, ZC3HAV1L | KMT2A 2179/4885NPSR1 2662/4885ALDH1A1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.