Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993711 | 0.81 | KDM4E (0.59) | TP53SMN1; SMN2CA12CA9TNKS2 | |
| SCHEMBL25325339 | 0.81 | TP53 (0.55) | TP53SMN1; SMN2CA12CA9TNKS2 | |
| SCHEMBL30501990 | 0.81 | TP53 (0.55) | TP53SMN1; SMN2CA12CA9TNKS2 | |
| SCHEMBL8873180 | 0.79 | CA12 (0.56) | TP53SMN1; SMN2CA12CA9MAPT | |
| SCHEMBL30908654 | 0.78 | CA12 (0.46) | TP53SMN1; SMN2CA12CA9TNKS2 | |
| SCHEMBL30908532 | 0.78 | TNKS2 (0.46) | TP53SMN1; SMN2CA12CA9TNKS2 | |
| SCHEMBL15448464 | 0.78 | CA12 (0.46) | TP53SMN1; SMN2CA12CA9TNKS2 | |
| SCHEMBL25404044 | 0.76 | TNKS2 (0.58) | TP53SMN1; SMN2TNKS2MAPTLMNA | |
| SCHEMBL30759515 | 0.74 | TP53 (0.47) | TP53SMN1; SMN2TNKS2MAPTLMNA | |
| SCHEMBL29171685 | 0.74 | TP53 (0.47) | TP53SMN1; SMN2TNKS2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |