Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15448464 | 1.00 | CA12 (0.46) | CA12CA9ADORA1PDE3BPDE3A | |
| SCHEMBL5993711 | 0.81 | KDM4E (0.59) | CA12CA9PDE3BPDE3AKDM4E | |
| SCHEMBL2798796 | 0.79 | KDM4E (0.58) | PDE3BPDE3AKDM4EGLAGAA | |
| SCHEMBL30908532 | 0.78 | TNKS2 (0.46) | CA12CA9ADORA1PDE3BPDE3A | |
| SCHEMBL706680 | 0.78 | PDE3B (0.43) | ADORA1PDE3BPDE3AKDM4EGLA | |
| SCHEMBL30908192 | 0.78 | TP53 (0.51) | CA12CA9ADORA1PDE3BPDE3A | |
| SCHEMBL8873180 | 0.76 | CA12 (0.56) | CA12CA9ADORA1PDE3BPDE3A | |
| SCHEMBL15448463 | 0.74 | KDM4E (0.56) | CA12CA9PDE3BPDE3AKDM4E | |
| SCHEMBL30908311 | 0.74 | AR (0.58) | — | |
| SCHEMBL7265005 | 0.72 | PDE3B (0.49) | CA12CA9ADORA1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |