Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129547 | 1.00 | TDP1 (0.44) | TDP1ALDH1A1NPSR1MAPK1ATM | |
| SCHEMBL719802 | 0.84 | TDP1 (0.50) | TDP1ALDH1A1NPSR1MAPK1GAA | |
| SCHEMBL15582692 | 0.83 | GAA (0.49) | TDP1ALDH1A1MAPK1ATMGAA | |
| SCHEMBL6118870 | 0.83 | MAPK1 (0.44) | TDP1ALDH1A1MAPK1ATMGAA | |
| SCHEMBL27416287 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1NPSR1MAPK1KDM4E | |
| SCHEMBL4043719 | 0.81 | CSF1R (0.49) | ALDH1A1MAPK1ATMGAAKDM4E | |
| SCHEMBL31133019 | 0.81 | GAA (0.55) | ALDH1A1MAPK1ATMGAAKDM4E | |
| SCHEMBL31132686 | 0.81 | GAA (0.55) | ALDH1A1MAPK1ATMGAAKDM4E | |
| SCHEMBL29877970 | 0.81 | MAPK1 (0.42) | TDP1ALDH1A1MAPK1ATMGAA | |
| SCHEMBL31030191 | 0.80 | ALDH1A1 (0.51) | TDP1ALDH1A1NPSR1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |