Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16938454 | 0.89 | BRD4 (0.61) | KDM4EALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL14473810 | 0.86 | PKN1 (0.62) | KDM4EALDH1A1L3MBTL1HPGDHSD17B10 | |
| SCHEMBL4243540 | 0.84 | HSP90AA1 (0.69) | KDM4EALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL27077574 | 0.84 | TDP1 (0.69) | KDM4EALDH1A1PARP1HSP90AA1ESR2 | |
| SCHEMBL29396281 | 0.83 | HTT (0.59) | KDM4EALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL22963740 | 0.83 | HTT (0.59) | KDM4EALDH1A1HTTLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7324046 | 0.82 | HSP90AA1 (0.68) | KDM4EALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL22912783 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL22963743 | 0.81 | HTT (0.56) | KDM4EALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL29397532 | 0.81 | HTT (0.56) | KDM4EALDH1A1HTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |