Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | NQO2 | P16083 | 6/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4589419 | 0.80 | CA12 (0.53) | CYP19A1NQO2CA12CA9CA1 | |
| SCHEMBL12569582 | 0.76 | CA12 (0.47) | CA12CA9CA1CA3CA4 | |
| SCHEMBL3784446 | 0.75 | CA12 (0.55) | CYP19A1NQO2CA12CA9CA1 | |
| SCHEMBL29153237 | 0.73 | CA12 (0.53) | CA12CA9CA1CA3CA4 | |
| SCHEMBL13524439 | 0.73 | CYP19A1 (0.47) | CYP19A1NQO2CA12CA9KDM4E | |
| SCHEMBL30516741 | 0.73 | STING1 (0.40) | CA12CA9KDM4EALDH1A1HPGD | |
| SCHEMBL6378203 | 0.73 | CA12 (0.45) | CYP19A1NQO2CA12CA9 | |
| SCHEMBL433883 | 0.71 | CA12 (0.60) | CA12CA9CA1CA3CA4 | |
| SCHEMBL30063823 | 0.71 | CA12 (0.60) | CA12CA9CA1CA3CA4 | |
| SCHEMBL21642314 | 0.70 | GRIN2D (0.46) | CYP19A1NQO2KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |