Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25953861 | 0.89 | MAPK1 (0.49) | MAPK1KDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL24933715 | 0.89 | MAPK1 (0.49) | MAPK1KDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL12791697 | 0.85 | MAPK1 (0.46) | MAPK1KDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL4636166 | 0.84 | MAPK1 (0.45) | MAPK1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL27810918 | 0.81 | ALDH1A1 (0.45) | MAPK1KDM4EL3MBTL1ALDH1A1HPGD | |
| SCHEMBL64188 | 0.81 | PLAT (0.43) | MAPK1KDM4EL3MBTL1ALDH1A1HPGDS | |
| SCHEMBL63803 | 0.80 | MAPK1 (0.41) | MAPK1KDM4EL3MBTL1HPGDOPRK1 | |
| SCHEMBL2636813 | 0.76 | MAPK1 (0.41) | MAPK1KDM4EL3MBTL1 | |
| SCHEMBL30908584 | 0.75 | MAPK1 (0.42) | MAPK1KDM4EL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL31705854 | 0.75 | ATM (0.50) | MAPK1ALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |