SCHEMBL30908490

SCHEMBL30908490

CCOC(=O)/C=C/c1cnc(C(=O)OC)cc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.46
CNKSR1 Q969H4 1/20 0.42
FDPS P14324 1/20 0.41
ESR1 P03372 1/20 0.40
CCNC P24863 4/20 0.40
CDK8 P49336 4/20 0.40
TTR P02766 1/20 0.40
MAOB P27338 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
MAPK1 P28482 1/20 0.39
CYP3A4 P08684 1/20 0.39
P2RY12 Q9H244 1/20 0.38
CDK19 Q9BWU1 1/20 0.38
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5371971 0.84 DPP4 (0.47) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL5371975 0.84 DPP4 (0.47) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL30645895 0.83 DPP4 (0.49) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL23705853 0.82 CNKSR1 (0.46) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL29673307 0.82 CNKSR1 (0.46) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL5363556 0.82 DPP4 (0.45) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL30103131 0.82 CNKSR1 (0.46) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL15507174 0.82 CNKSR1 (0.46) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL29838567 0.82 DPP4 (0.45) DPP4CNKSR1FDPSESR1CCNC
SCHEMBL5363535 0.82 DPP4 (0.45) DPP4CNKSR1FDPSESR1CCNC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074611-A1 PRMT5 INHIBITORS Ryvu Therapeutics S.A. (PL) 2024-04-11 WO disclosed